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PPM1D

Description protein phosphatase, Mg2+/Mn2+ dependent 1D
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • Protein Serine/threonine Phosphatase Activity
  • Magnesium-dependent Protein Serine/threonine Phosphatase Activity
  • Protein Binding
  • Metal Ion Binding
  • Mitogen-activated Protein Kinase Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • DNA Methylation
  • Chromatin Silencing
  • Transcription Initiation From RNA Polymerase II Promoter
  • Protein Phosphorylation
  • Protein Dephosphorylation
  • Negative Regulation Of Cell Proliferation
  • Cellular Response To Starvation
  • Response To Radiation
  • Response To Bacterium
  • DNA Damage Response, Signal Transduction By P53 Class Mediator
  • Peptidyl-threonine Dephosphorylation
  • Negative Regulation Of Gene Expression, Epigenetic
Pathways
  • Transcriptional regulation by RUNX2
Drugs
Diseases
GWAS
  • Blood urea nitrogen levels ( 31152163)
Interacting Genes 25 interacting genes: ATP6V1A BEX2 CASZ1 CHEK2 DIRAS3 DKK3 EPSTI1 ERRFI1 GLCE H3-3A H3C1 ITIH5 KDM1A LYPD3 MAPK11 MDM2 MRC2 NAT2 NCL NSD3 OSGIN1 RHOBTB2 RPL5 TP53 UBC
Entrez ID 8493
HPRD ID 05482
Ensembl ID ENSG00000170836
Uniprot IDs A0A0S2Z4M2 O15297
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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