GRHPR and LSM1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		GRHPR	LSM1
Description		glyoxylate and hydroxypyruvate reductase	LSM1 homolog, mRNA degradation associated
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome Catalytic Complex	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Glycerate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP) Activity Carboxylic Acid Binding Protein Homodimerization Activity NAD Binding NADPH Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Excretion Cellular Nitrogen Compound Metabolic Process Dicarboxylic Acid Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways		Glyoxylate metabolism and glycine degradation	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases		Primary hyperoxaluria (HP)
GWAS		Bipolar disorder ( 31043756) Chronotype ( 30696823) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		6 interacting genes: CDC7 FOS GLS2 LIG4 LSM1 PTH2R	27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		9380	27257
HPRD ID		05052	06281
Ensembl ID		ENSG00000137106	ENSG00000175324
Uniprot IDs		A0A384N605 Q9UBQ7	A0A0S2Z590 O15116
PDB IDs		2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?
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