GRHPR and PTH2R

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GRHPR	PTH2R
Description		glyoxylate and hydroxypyruvate reductase	parathyroid hormone 2 receptor
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome Catalytic Complex	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Glycerate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP) Activity Carboxylic Acid Binding Protein Homodimerization Activity NAD Binding NADPH Binding	Parathyroid Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Excretion Cellular Nitrogen Compound Metabolic Process Dicarboxylic Acid Metabolic Process Glyoxylate Metabolic Process Oxidation-reduction Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways		Glyoxylate metabolism and glycine degradation	Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Parathyroid hormone
Diseases		Primary hyperoxaluria (HP)
GWAS		Bipolar disorder ( 31043756) Chronotype ( 30696823) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anthropometric traits ( 30576415) Metabolite levels ( 23823483) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744)
Interacting Genes		6 interacting genes: CDC7 FOS GLS2 LIG4 LSM1 PTH2R	5 interacting genes: CALM1 GRHPR HMG20A PTH PTH2
Entrez ID		9380	5746
HPRD ID		05052	03276
Ensembl ID		ENSG00000137106	ENSG00000144407
Uniprot IDs		A0A384N605 Q9UBQ7	B4DFN8 P49190
PDB IDs		2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?
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