LSM1 and MPDU1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
BioGRID (two hybrid)

		LSM1	MPDU1
Description		LSM1 homolog, mRNA degradation associated	mannose-P-dolichol utilization defect 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Protein Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Protein Folding Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide Biosynthetic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	IgA nephropathy ( 22197929)
Interacting Genes		27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11	2 interacting genes: LSM1 SHBG
Entrez ID		27257	9526
HPRD ID		06281	04951
Ensembl ID		ENSG00000175324	ENSG00000129255
Uniprot IDs		A0A0S2Z590 O15116	A0A0S2Z4W8 B4DLH7 J3QW43 O75352
PDB IDs
Enriched GO Terms of Interacting Partners?
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