LSM1 and NARS1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		LSM1	NARS1
Description		LSM1 homolog, mRNA degradation associated	asparaginyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Nucleic Acid Binding Asparagine-tRNA Ligase Activity ATP Binding CCR3 Chemokine Receptor Binding Protein Dimerization Activity
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation Cell Migration
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	Cytosolic tRNA aminoacylation
Drugs			L-Asparagine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11	3 interacting genes: ATXN1 HSPB2 LSM1
Entrez ID		27257	4677
HPRD ID		06281	00154
Ensembl ID		ENSG00000175324	ENSG00000134440
Uniprot IDs		A0A0S2Z590 O15116	O43776
PDB IDs			4ZYA 5XIX
Enriched GO Terms of Interacting Partners?
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