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LSM1

Description LSM1 homolog, mRNA degradation associated
Image No pdb structure
GO Annotations Cellular Component
  • P-body
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Axon
  • Dendrite
  • Neuronal Cell Body
  • Messenger Ribonucleoprotein Complex
  • Lsm1-7-Pat1 Complex
Molecular Function
  • RNA Cap Binding
  • RNA Binding
  • MRNA Binding
  • Protein Binding
  • Pre-mRNA Binding
Biological Process
  • Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
  • RNA Splicing, Via Transesterification Reactions
  • MRNA Processing
  • RNA Splicing
  • RNA Metabolic Process
  • Stem Cell Population Maintenance
  • Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
  • Negative Regulation Of Neuron Differentiation
  • Histone MRNA Catabolic Process
Pathways
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes 27 interacting genes: CLIC1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID 27257
HPRD ID 06281
Ensembl ID ENSG00000175324
Uniprot IDs A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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