PEA15 and OSBPL1A

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	OSBPL1A
Description		proliferation and apoptosis adaptor protein 15	oxysterol binding protein like 1A
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Late Endosome Cytosol Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Phospholipid Binding Lipid Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Bile Acid Biosynthetic Process Cholesterol Metabolic Process Sterol Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Synthesis of bile acids and bile salts MHC class II antigen presentation
Drugs
Diseases
GWAS			Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Osteoporosis-related phenotypes ( 20548944) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25483131)
Interacting Genes		39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	4 interacting genes: BAALC PEA15 TIAM1 TSC22D2
Entrez ID		8682	114876
HPRD ID		04579	09472
Ensembl ID		ENSG00000162734	ENSG00000141447
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	B0YJ56 B3KU11 Q6GSK5 Q9BXW6
PDB IDs		4IZ5 4IZA 6P6B 6P6C	5ZM5 5ZM6 5ZM7 6IYB
Enriched GO Terms of Interacting Partners?
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