PEA15 and ABCD4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PEA15	ABCD4
Description		proliferation and apoptosis adaptor protein 15	ATP binding cassette subfamily D member 4
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Lysosomal Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane ATP-binding Cassette (ABC) Transporter Complex
	Molecular Function	Protein Binding	ATP Binding ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Cobalamin Metabolic Process Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Cobalamin (Cbl, vitamin B12) transport and metabolism Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ)
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	5 interacting genes: DLEU1 HSPB2 PEA15 SARAF XRCC6
Entrez ID		8682	5826
HPRD ID		04579	04446
Ensembl ID		ENSG00000162734	ENSG00000119688
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	A0A024R6B9 O14678
PDB IDs		4IZ5 4IZA 6P6B 6P6C	6JBJ
Enriched GO Terms of Interacting Partners?
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