PEA15 and MTIF3

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	MTIF3
Description		proliferation and apoptosis adaptor protein 15	mitochondrial translational initiation factor 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Mitochondrion
	Molecular Function	Protein Binding	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding
	Biological Process	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Ribosome Disassembly Mitochondrial Translational Initiation
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Mitochondrial translation initiation
Drugs
Diseases
GWAS			BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)
Interacting Genes		39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	5 interacting genes: FBXO7 MAPK1 PAXIP1 PEA15 SIAH1
Entrez ID		8682	219402
HPRD ID		04579	17609
Ensembl ID		ENSG00000162734	ENSG00000122033
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	Q9H2K0
PDB IDs		4IZ5 4IZA 6P6B 6P6C	6NEQ 6NF8
Enriched GO Terms of Interacting Partners?
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