PEA15 and TALDO1

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	TALDO1
Description		proliferation and apoptosis adaptor protein 15	transaldolase 1
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Intracellular Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate Glyceronetransferase Activity Protein Binding Monosaccharide Binding
	Biological Process	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Carbohydrate Metabolic Process Xylulose Biosynthetic Process Fructose 6-phosphate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Glyceraldehyde-3-phosphate Metabolic Process Interleukin-12-mediated Signaling Pathway
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Insulin effects increased synthesis of Xylulose-5-Phosphate TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P Pentose phosphate pathway Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Proteinuria and chronic kidney disease ( 26420894)
Interacting Genes		39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	7 interacting genes: LSM8 PEA15 TERF1 TERF2 TERF2IP UBE3A ZHX1
Entrez ID		8682	6888
HPRD ID		04579	03640
Ensembl ID		ENSG00000162734	ENSG00000177156
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	A0A140VK56 P37837
PDB IDs		4IZ5 4IZA 6P6B 6P6C	1F05
Enriched GO Terms of Interacting Partners?
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