OSBPL1A and PEA15

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		OSBPL1A	PEA15
Description		oxysterol binding protein like 1A	proliferation and apoptosis adaptor protein 15
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GO Annotations	Cellular Component	Late Endosome Cytosol Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleoplasm Cytosol Microtubule Associated Complex
	Molecular Function	Protein Binding Phospholipid Binding Lipid Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding	Protein Binding
	Biological Process	Bile Acid Biosynthetic Process Cholesterol Metabolic Process Sterol Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Synthesis of bile acids and bile salts MHC class II antigen presentation	RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Osteoporosis-related phenotypes ( 20548944) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25483131)
Interacting Genes		4 interacting genes: BAALC PEA15 TIAM1 TSC22D2	39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		114876	8682
HPRD ID		09472	04579
Ensembl ID		ENSG00000141447	ENSG00000162734
Uniprot IDs		B0YJ56 B3KU11 Q6GSK5 Q9BXW6	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs		5ZM5 5ZM6 5ZM7 6IYB	4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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