TMEM79 and SFTPC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		TMEM79	SFTPC
Description		transmembrane protein 79	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Trans-Golgi Network Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification	Respiratory Gaseous Exchange Cellular Protein Metabolic Process
Pathways			Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		14 interacting genes: ABO CLEC7A PLN PLP2 RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMPRSS4 TNMD	12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2
Entrez ID		84283	6440
HPRD ID		17481	01520
Ensembl ID		ENSG00000163472	ENSG00000168484
Uniprot IDs		Q9BSE2	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
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