SFTPC and TMEM79

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		SFTPC	TMEM79
Description		surfactant protein C	transmembrane protein 79
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen	Lysosomal Membrane Integral Component Of Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Respiratory Gaseous Exchange Cellular Protein Metabolic Process	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification
Pathways		Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases		Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)	Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2	14 interacting genes: ABO CLEC7A PLN PLP2 RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMPRSS4 TNMD
Entrez ID		6440	84283
HPRD ID		01520	17481
Ensembl ID		ENSG00000168484	ENSG00000163472
Uniprot IDs		A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686	Q9BSE2
PDB IDs		2YAD
Enriched GO Terms of Interacting Partners?
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