SFTPC and SEC22A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SFTPC	SEC22A
Description		surfactant protein C	SEC22 homolog A, vesicle trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Transporter Activity Protein Binding
	Biological Process	Respiratory Gaseous Exchange Cellular Protein Metabolic Process	ER To Golgi Vesicle-mediated Transport Protein Transport
Pathways		Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)	COPII-mediated vesicle transport
Drugs
Diseases		Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2	11 interacting genes: DTX2 EDA ERLIN1 FATE1 LMNA MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79
Entrez ID		6440	26984
HPRD ID		01520	15313
Ensembl ID		ENSG00000168484	ENSG00000121542
Uniprot IDs		A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686	Q96IW7
PDB IDs		2YAD
Enriched GO Terms of Interacting Partners?
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