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SFTPC

Description surfactant protein C
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Endoplasmic Reticulum Membrane
  • Lamellar Body
  • Clathrin-coated Endocytic Vesicle
  • Multivesicular Body Lumen
Molecular Function
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Respiratory Gaseous Exchange
  • Cellular Protein Metabolic Process
Pathways
  • Surfactant metabolism
  • Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS)
  • Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)
  • Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases
  • Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS
  • Coronary artery disease ( 29212778)
  • Hypertriglyceridemia ( 23505323)
Interacting Genes 12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2
Entrez ID 6440
HPRD ID 01520
Ensembl ID ENSG00000168484
Uniprot IDs A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs 2YAD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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