SPTBN2 and MINK1

Number of citations of the paper that reports this interaction (PubMedID 15032605)
1

Data Source:
HPRD (two hybrid)

		SPTBN2	MINK1
Description		spectrin beta, non-erythrocytic 2	misshapen like kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Spectrin Apical Plasma Membrane Cell Junction Neuronal Cell Body Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Postsynaptic Spectrin-associated Cytoskeleton	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Cell Junction Axon Dendrite Extracellular Exosome
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding Cadherin Binding Structural Constituent Of Synapse	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping Postsynapse Organization	Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Mitotic Cell Cycle Regulation Of Cell-cell Adhesion Signal Transduction By Protein Phosphorylation Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity
Pathways		MHC class II antigen presentation NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport	Oxidative Stress Induced Senescence
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bipolar disorder ( 28115744 21926972 31043756)	Intracranial aneurysm ( 30823506) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Metabolite levels (lipid measures) ( 27005778) Multiple sclerosis ( 31604244)
Interacting Genes		10 interacting genes: ACTA1 ACTB ACTR1A APC CELSR3 DCTN1 MINK1 SPTA1 SPTAN1 UNC13B	14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		6712	50488
HPRD ID		05404	11366
Ensembl ID		ENSG00000173898	ENSG00000141503
Uniprot IDs		O15020	Q8N4C8
PDB IDs		1WJM 1WYQ 6ANU
Enriched GO Terms of Interacting Partners?
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