MINK1 and ABI1

Number of citations of the paper that reports this interaction (PubMedID 15032605)
1

Data Source:
HPRD (two hybrid)

		MINK1	ABI1
Description		misshapen like kinase 1	abl interactor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Cell Junction Axon Dendrite Extracellular Exosome	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Aggresome Lamellipodium Cell Junction Growth Cone SCAR Complex Filopodium Tip Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Protein Tyrosine Kinase Activator Activity Cadherin Binding
	Biological Process	Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Mitotic Cell Cycle Regulation Of Cell-cell Adhesion Signal Transduction By Protein Phosphorylation Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity	Somitogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Viral Process Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Dendrite Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis
Pathways		Oxidative Stress Induced Senescence	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Intracranial aneurysm ( 30823506) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Metabolite levels (lipid measures) ( 27005778) Multiple sclerosis ( 31604244)
Interacting Genes		14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ	29 interacting genes: ABL1 APBB1 CACNA1A CUL2 CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PCM1 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2
Entrez ID		50488	10006
HPRD ID		11366	04336
Ensembl ID		ENSG00000141503	ENSG00000136754
Uniprot IDs		Q8N4C8	A0A0A0MRT6 B6VEX3 B6VEX4 B6VEX5 Q8IZP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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