MINK1 and SPTBN2

Number of citations of the paper that reports this interaction (PubMedID 15032605)
1

Data Source:
HPRD (two hybrid)

		MINK1	SPTBN2
Description		misshapen like kinase 1	spectrin beta, non-erythrocytic 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Cell Junction Axon Dendrite Extracellular Exosome	Extracellular Space Cytosol Spectrin Apical Plasma Membrane Cell Junction Neuronal Cell Body Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Postsynaptic Spectrin-associated Cytoskeleton
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding Cadherin Binding Structural Constituent Of Synapse
	Biological Process	Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Mitotic Cell Cycle Regulation Of Cell-cell Adhesion Signal Transduction By Protein Phosphorylation Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping Postsynapse Organization
Pathways		Oxidative Stress Induced Senescence	MHC class II antigen presentation NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Intracranial aneurysm ( 30823506) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Metabolite levels (lipid measures) ( 27005778) Multiple sclerosis ( 31604244)	Bipolar disorder ( 28115744 21926972 31043756)
Interacting Genes		14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ	10 interacting genes: ACTA1 ACTB ACTR1A APC CELSR3 DCTN1 MINK1 SPTA1 SPTAN1 UNC13B
Entrez ID		50488	6712
HPRD ID		11366	05404
Ensembl ID		ENSG00000141503	ENSG00000173898
Uniprot IDs		Q8N4C8	O15020
PDB IDs			1WJM 1WYQ 6ANU
Enriched GO Terms of Interacting Partners?
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