SEC22A and SFTPC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC22A	SFTPC
Description		SEC22 homolog A, vesicle trafficking protein	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Multivesicular Body Lumen
	Molecular Function	Transporter Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Transport	Respiratory Gaseous Exchange Cellular Protein Metabolic Process
Pathways		COPII-mediated vesicle transport	Surfactant metabolism Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		11 interacting genes: DTX2 EDA ERLIN1 FATE1 LMNA MSR1 RNF5 SFTPC STX4 SYNE4 TMEM79	12 interacting genes: CREB3 CXCL9 LMNA NEDD4 PQBP1 SEC22A SEC61G SMIM3 SYNE4 TMEM79 WWP1 WWP2
Entrez ID		26984	6440
HPRD ID		15313	01520
Ensembl ID		ENSG00000121542	ENSG00000168484
Uniprot IDs		Q96IW7	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
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