XPNPEP3 and CYB5R3

		XPNPEP3	CYB5R3
Description		X-prolyl aminopeptidase 3	cytochrome b5 reductase 3
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen
	Molecular Function	Aminopeptidase Activity Protein Binding Manganese Ion Binding Protein Homodimerization Activity Metalloaminopeptidase Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding
	Biological Process	Glomerular Filtration Proteolysis Protein Processing	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process
Pathways			Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases		Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)	Methemoglobinemia
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) C-reactive protein levels ( 30388399) Experiencing mood swings ( 29500382) Schizophrenia ( 28991256)	Initial pursuit acceleration ( 29064472)
Interacting Genes		1 interacting genes: CYB5R3	11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3
Entrez ID		63929	1727
HPRD ID		10052	08942
Ensembl ID		ENSG00000196236	ENSG00000100243
Uniprot IDs		A0A087X0Z2 Q9NQH7	P00387
PDB IDs		5X49	1M91 1UMK
Enriched GO Terms of Interacting Partners?
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