VPS52 and HEATR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS52	HEATR1
Description		VPS52 subunit of GARP complex	HEAT repeat containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex	Fibrillar Center Nucleoplasm Nucleolus Mitochondrion Membrane 90S Preribosome Small-subunit Processome T-UTP Complex
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of RRNA Processing
Pathways		Retrograde transport at the Trans-Golgi-Network	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)	Post bronchodilator FEV1/FVC ratio ( 26634245) Total cholesterol levels ( 30275531)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	4 interacting genes: AAGAB VPS52 XRN1 YIF1A
Entrez ID		6293	55127
HPRD ID		09142	10962
Ensembl ID		ENSG00000223501	ENSG00000119285
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	A2VDI1 B2RWN5 Q9H583
PDB IDs
Enriched GO Terms of Interacting Partners?
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