VPS52 and MFAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS52	MFAP1
Description		VPS52 subunit of GARP complex	microfibril associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex	Microfibril Extracellular Region Nucleus Nucleoplasm Centrosome U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	RNA Binding Protein Binding
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	MRNA Splicing, Via Spliceosome
Pathways		Retrograde transport at the Trans-Golgi-Network	Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)	Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	47 interacting genes: AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 LMNA MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SNIP1 SNW1 SSX2IP STX11 TADA2A TLE5 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398
Entrez ID		6293	4236
HPRD ID		09142	02569
Ensembl ID		ENSG00000223501	ENSG00000140259
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	P55081
PDB IDs			5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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