VPS52 and TBC1D22B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS52	TBC1D22B
Description		VPS52 subunit of GARP complex	TBC1 domain family member 22B
Image		No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding 14-3-3 Protein Binding
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)	Acne (severe) ( 24927181) Platelet count ( 27863252)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	23 interacting genes: CALCOCO2 CCDC57 CDR2 DAPK1 DEUP1 FXR2 GOLGA2 HSD17B14 IKZF3 KRT40 LRRK2 MFHAS1 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52
Entrez ID		6293	55633
HPRD ID		09142	15475
Ensembl ID		ENSG00000223501	ENSG00000065491
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	Q9NU19
PDB IDs			6D0S
Enriched GO Terms of Interacting Partners?
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