VPS52 and VPS53

Number of citations of the paper that reports this interaction (PubMedID 15878329)
45

Data Source:
HPRD (in vitro, in vivo)

		VPS52	VPS53
Description		VPS52 subunit of GARP complex	VPS53 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	Protein Binding
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	Lysosomal Transport Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)	Decline in glucose metabolism in posterior cingulate cortex ( 29130521) HDL cholesterol ( 30275531) Prostate cancer ( 23535732) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	2 interacting genes: EXOC2 VPS52
Entrez ID		6293	55275
HPRD ID		09142	07720
Ensembl ID		ENSG00000223501	ENSG00000141252
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	B3KS06 Q5VIR6
PDB IDs
Enriched GO Terms of Interacting Partners?
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