HEATR1 and VPS52

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HEATR1	VPS52
Description		HEAT repeat containing 1	VPS52 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Mitochondrion Membrane 90S Preribosome Small-subunit Processome T-UTP Complex	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding	Protein Binding Rab GTPase Binding Syntaxin Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of RRNA Processing	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Total cholesterol levels ( 30275531)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		4 interacting genes: AAGAB VPS52 XRN1 YIF1A	50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2
Entrez ID		55127	6293
HPRD ID		10962	09142
Ensembl ID		ENSG00000119285	ENSG00000223501
Uniprot IDs		A2VDI1 B2RWN5 Q9H583	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?
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