MAP1LC3C and MEFV

Number of citations of the paper that reports this interaction (PubMedID 26347139)
65

Data Source:
BioGRID (pull down)

		MAP1LC3C	MEFV
Description		microtubule associated protein 1 light chain 3 gamma	MEFV innate immuity regulator, pyrin
Image
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Ruffle Nucleus Nucleoplasm Cytoplasm Autophagosome Cytosol Microtubule Microtubule Associated Complex Lamellipodium Cytoplasmic Vesicle
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Actin Binding Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Inflammatory Response Positive Regulation Of Autophagy Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-12 Production Response To Interferon-gamma Negative Regulation Of Inflammatory Response Negative Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity
Pathways		Macroautophagy	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Familial Mediterranean fever (FMF); Familial hereditary periodic fever syndromes
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)	Ankylosing spondylitis ( 30946743)
Interacting Genes		19 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B CUL3 KBTBD6 KBTBD7 LMNB1 MEFV NEDD4 OPTN RB1CC1 SQSTM1 TAX1BP1 TRIM21 ULK1 WDFY3 WDR81	12 interacting genes: COG5 GABARAP GABARAPL1 GABARAPL2 LGALS3 LGALS8 MAP1LC3A MAP1LC3C PSTPIP1 PYCARD SIVA1 ULK1
Entrez ID		440738	4210
HPRD ID		14226	02012
Ensembl ID		ENSG00000197769	ENSG00000103313
Uniprot IDs		Q9BXW4	D2DTW2 O15553
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW	2MPC 2WL1 4CG4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?