MAP1LC3C and LMNB1

Number of citations of the paper that reports this interaction (PubMedID 26524528)
109

Data Source:
BioGRID (pull down)

		MAP1LC3C	LMNB1
Description		microtubule associated protein 1 light chain 3 gamma	lamin B1
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GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Interleukin-12-mediated Signaling Pathway
Pathways		Macroautophagy	Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		19 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B CUL3 KBTBD6 KBTBD7 LMNB1 MEFV NEDD4 OPTN RB1CC1 SQSTM1 TAX1BP1 TRIM21 ULK1 WDFY3 WDR81	29 interacting genes: ABCG8 ATF4 CASP3 CASP6 CDK1 GABARAP GIT2 GZMA GZMB LBR LMNA MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PLEC PRKCA PRKCB PRKCD PRPH RNF123 SERPINA3 SRPK2 SUMO4 TMPO TOR1AIP1 URB2 YWHAQ
Entrez ID		440738	4001
HPRD ID		14226	01036
Ensembl ID		ENSG00000197769	ENSG00000113368
Uniprot IDs		Q9BXW4	B4DZT3 P20700
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW	2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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