TRIM69 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TRIM69	PPP1R18
Description		tripartite motif containing 69	protein phosphatase 1 regulatory subunit 18
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Cytoplasm Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730)
Interacting Genes		28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483	37 interacting genes: CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KASH5 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52
Entrez ID		140691	170954
HPRD ID		11518	11172
Ensembl ID		ENSG00000185880	ENSG00000146112
Uniprot IDs		H0YL66 Q86WT6	A0A024RCJ8 Q6NYC8
PDB IDs		4NQJ
Enriched GO Terms of Interacting Partners?
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