TRIM69 and SF3A3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		TRIM69	SF3A3
Description		tripartite motif containing 69	splicing factor 3a subunit 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process	RNA Splicing, Via Transesterification Reactions MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	mRNA Splicing - Major Pathway
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418)
Interacting Genes		28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483	18 interacting genes: ADAP1 APBB1 APP CCDC85B HSPB1 MTNR1B PRMT5 PRPF40A SF3A1 SREK1 TADA2A TCERG1 TRIM69 U2AF1 VAV2 WBP4 ZDHHC17 ZNF212
Entrez ID		140691	10946
HPRD ID		11518	10411
Ensembl ID		ENSG00000185880	ENSG00000183431
Uniprot IDs		H0YL66 Q86WT6	B4DW90 Q12874
PDB IDs		4NQJ	2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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