TRIM69 and ASNS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM69	ASNS
Description		tripartite motif containing 69	asparagine synthetase (glutamine-hydrolyzing)
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Asparagine Synthase (glutamine-hydrolyzing) Activity Protein Binding ATP Binding Identical Protein Binding Cofactor Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process	Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus PERK-mediated Unfolded Protein Response Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	ATF4 activates genes in response to endoplasmic reticulum stress Aspartate and asparagine metabolism Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs			L-Aspartic Acid Glutamic Acid ATP L-Asparagine
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Regular attendance at a religious group ( 29970889) Tuberculosis ( 30713548)
Interacting Genes		28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483	5 interacting genes: ATXN1 RAB8A STRN4 TRIM69 WDR27
Entrez ID		140691	440
HPRD ID		11518	00153
Ensembl ID		ENSG00000185880	ENSG00000070669
Uniprot IDs		H0YL66 Q86WT6	P08243
PDB IDs		4NQJ	6GQ3
Enriched GO Terms of Interacting Partners?
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