SEC61B and GET3

Number of citations of the paper that reports this interaction (PubMedID 20676083)
113

Data Source:
BioGRID (pull down, pull down)

		SEC61B	GET3
Description		SEC61 translocon subunit beta	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	RNA Binding ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Epidermal Growth Factor Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS		Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A	14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2
Entrez ID		10952	439
HPRD ID		06715	03555
Ensembl ID		ENSG00000106803	ENSG00000198356
Uniprot IDs		P60468	O43681
PDB IDs
Enriched GO Terms of Interacting Partners?
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