GET3 and GPX7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		GET3	GPX7
Description		guided entry of tail-anchored proteins factor 3, ATPase	glutathione peroxidase 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane	Cellular Response To Oxidative Stress Oxidation-reduction Process Cellular Oxidant Detoxification
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Detoxification of Reactive Oxygen Species
Drugs		ATP	Glutathione
Diseases
GWAS			Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2	6 interacting genes: CEP70 CPEB2 ERO1A GET3 SGTA UBQLN4
Entrez ID		439	2882
HPRD ID		03555	13606
Ensembl ID		ENSG00000198356	ENSG00000116157
Uniprot IDs		O43681	Q96SL4
PDB IDs			2P31
Enriched GO Terms of Interacting Partners?
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