SEC61B and GET4

Number of citations of the paper that reports this interaction (PubMedID 20676083)
113

Data Source:
BioGRID (pull down)

		SEC61B	GET4
Description		SEC61 translocon subunit beta	guided entry of tail-anchored proteins factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Nucleoplasm Nucleolus Cytoplasm Cytosol BAT3 Complex
	Molecular Function	RNA Binding ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Epidermal Growth Factor Binding	Protein Binding Chaperone Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A	21 interacting genes: AKT1 ATP5PD BAG6 CAPNS1 CDKN1A CEP126 EEF1G FLYWCH2 GET3 KAT5 KIFC2 PLK1 PRKAB2 PRKCSH PTMS SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2
Entrez ID		10952	51608
HPRD ID		06715	12909
Ensembl ID		ENSG00000106803	ENSG00000239857
Uniprot IDs		P60468	Q7L5D6
PDB IDs			6AU8
Enriched GO Terms of Interacting Partners?
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