SEC61B and SERP1

Number of citations of the paper that reports this interaction (PubMedID 10601334)
29

Data Source:
HPRD (in vivo)

		SEC61B	SERP1
Description		SEC61 translocon subunit beta	stress associated endoplasmic reticulum protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function	RNA Binding ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Epidermal Growth Factor Binding	Protein Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Plasma Membrane Organization Post-embryonic Development Multicellular Organism Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion IRE1-mediated Unfolded Protein Response Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion
Pathways		ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A	8 interacting genes: APP CANX LMNA SCNN1A SCNN1G SEC61A1 SEC61B TMEM79
Entrez ID		10952	27230
HPRD ID		06715	18037
Ensembl ID		ENSG00000106803	ENSG00000120742
Uniprot IDs		P60468	Q9Y6X1
PDB IDs
Enriched GO Terms of Interacting Partners?
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