GET3 and SEC61A1

Number of citations of the paper that reports this interaction (PubMedID 20676083)
113

Data Source:
BioGRID (pull down)

		GET3	SEC61A1
Description		guided entry of tail-anchored proteins factor 3, ATPase	SEC61 translocon subunit alpha 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Signal Sequence Binding Calcium Channel Activity Protein Binding Protein Transmembrane Transporter Activity Ribosome Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Posttranslational Protein Targeting To Membrane, Translocation Response To Interferon-gamma Pronephric Nephron Development Protein Targeting To ER Calcium Ion Transmembrane Transport
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane
Drugs		ATP
Diseases
GWAS			Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		14 interacting genes: APLN ASPH CACNA1A GET4 GPX7 HILPDA PFDN1 SEC61A1 SEC61B STATH STX5 TK1 TTR VAMP2	9 interacting genes: ACAD9 BAG6 CALM1 GET3 HSPA5 MLH1 SEC61G SERP1 TNF
Entrez ID		439	29927
HPRD ID		03555	15316
Ensembl ID		ENSG00000198356	ENSG00000058262
Uniprot IDs		O43681	B3KME8 B3KNF6 P61619
PDB IDs
Enriched GO Terms of Interacting Partners?
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