| Novel |
CCR7
|
C-C motif chemokine receptor 7 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
|
|
|
| Novel |
CDC27
|
cell division cycle 27 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
| Novel |
CRHR1
|
corticotropin releasing hormone receptor 1 |
- Class B/2 (Secretin family receptors)
- G alpha (s) signalling events
|
- Corticorelin ovine triflutate
|
|
| Novel |
KRT13
|
keratin 13 |
- Keratinization
- Formation of the cornified envelope
|
|
|
| Novel |
MED1
|
mediator complex subunit 1 |
- BMAL1:CLOCK,NPAS2 activates circadian expression
- PPARA activates gene expression
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional activation of mitochondrial biogenesis
- Activation of gene expression by SREBF (SREBP)
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Nuclear Receptor transcription pathway
- Regulation of lipid metabolism by PPARalpha
- Estrogen-dependent gene expression
- Cytoprotection by HMOX1
- Heme signaling
- RSV-host interactions
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- Expression of BMAL (ARNTL), CLOCK, and NPAS2
- RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
AQP6
|
aquaporin 6 |
- Passive transport by Aquaporins
|
|
|
|
ARL13B
|
ARF like GTPase 13B |
- ARL13B-mediated ciliary trafficking of INPP5E
- RHOQ GTPase cycle
- RHOJ GTPase cycle
- Chaperone Mediated Autophagy
- Late endosomal microautophagy
- Aggrephagy
- Aggrephagy
|
|
|
|
C10orf67
|
chromosome 10 open reading frame 67 |
|
|
|
|
CERS3
|
ceramide synthase 3 |
- Sphingolipid de novo biosynthesis
|
|
|
|
COQ8A
|
coenzyme Q8A |
|
|
- Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
- Coenzyme Q10 deficiency
|
|
EBP
|
EBP cholestenol delta-isomerase |
- Cholesterol biosynthesis via desmosterol
- Cholesterol biosynthesis via lathosterol
|
|
|
|
EEF1A1
|
eukaryotic translation elongation factor 1 alpha 1 |
- Eukaryotic Translation Elongation
- Eukaryotic Translation Elongation
- Peptide chain elongation
- HSF1 activation
- Neutrophil degranulation
- Protein methylation
- Chaperone Mediated Autophagy
- SARS-CoV-1 modulates host translation machinery
|
- Zinc
- Guanosine-5'-Diphosphate
- Copper
- Artenimol
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
|
|
|
ELOVL4
|
ELOVL fatty acid elongase 4 |
- Synthesis of very long-chain fatty acyl-CoAs
|
|
- Stargardt disease (STGD); Fundus flavimaculatus
|
|
ERGIC3
|
ERGIC and golgi 3 |
|
|
|
|
FAM209A
|
family with sequence similarity 209 member A |
|
|
|
|
GET1
|
guided entry of tail-anchored proteins factor 1 |
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
|
|
|
|
GPR101
|
G protein-coupled receptor 101 |
|
|
|
|
GPR152
|
G protein-coupled receptor 152 |
|
|
|
|
HSD17B13
|
hydroxysteroid 17-beta dehydrogenase 13 |
- Lipid particle organization
|
|
|