ORMDL3

Gene Name		ORMDL sphingolipid biosynthesis regulator 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SPOTS Complex
	Molecular Function	Protein Binding
	Biological Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Asthma ( 21150878 17611496 22561531) Crohn's disease ( 18587394 21102463) Hematological parameters ( 19820697) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 23000144 21399635 20639880) Type 1 diabetes ( 19430480) Type 1 diabetes autoantibodies ( 21829393) Ulcerative colitis ( 20228799 21297633) White blood cell count ( 21738480)
Protein-protein Interactions		3 interactors: APP EEF1A1 LNX1
Entrez ID		94103
HPRD ID		17803
Ensembl ID		ENSG00000172057
Uniprot IDs		Q8N138
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling
Tagcloud ?		analogous anthers fertile fertility grown loc normally orms orosomucoids ortholog os07g26940 panicles perturbed plants pollen polypeptides resisdent rice rnai rooms sphingolipid sphingolipids sterile sterility suppressing tgms tms2