NEU1 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	CDC42SE2	CDC42 small effector 2	CDC42 GTPase cycle
Novel	IGF1	insulin like growth factor 1	Platelet degranulation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) IRS-related events triggered by IGF1R SHC-related events triggered by IGF1R Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Synthesis, secretion, and deacylation of Ghrelin	N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate	Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD) Malignant pleural mesothelioma
Novel	MAF	MAF bZIP transcription factor	RUNX2 regulates osteoblast differentiation		Multiple myeloma
Novel	MSH5	mutS homolog 5	Meiotic recombination
Novel	NFYA	nuclear transcription factor Y subunit alpha	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Novel	NOTCH4	notch receptor 4	Pre-NOTCH Processing in the Endoplasmic Reticulum Pre-NOTCH Transcription and Translation Pre-NOTCH Processing in Golgi Pre-NOTCH Processing in Golgi Notch-HLH transcription pathway Defective LFNG causes SCDO3 NOTCH4 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription NOTCH4 Activation and Transmission of Signal to the Nucleus NOTCH4 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling Negative regulation of NOTCH4 signaling
Novel	PBX2	PBX homeobox 2
Novel	SLC17A2	solute carrier family 17 member 2
	AQP6	aquaporin 6	Passive transport by Aquaporins
	CCR9	C-C motif chemokine receptor 9	Chemokine receptors bind chemokines G alpha (i) signalling events	Vercirnon
	CD79A	CD79a molecule	CD22 mediated BCR regulation Potential therapeutics for SARS Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
	CERS3	ceramide synthase 3	Sphingolipid de novo biosynthesis
	CERS4	ceramide synthase 4	Sphingolipid de novo biosynthesis
	CREB3	cAMP responsive element binding protein 3	CREB3 factors activate genes CREB3 factors activate genes
	CREB3L1	cAMP responsive element binding protein 3 like 1	CREB3 factors activate genes
	CTSA	cathepsin A	MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation Glycosphingolipid catabolism		Galactosialidosis
	EBP	EBP cholestenol delta-isomerase	Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol	Tamoxifen
	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy SARS-CoV-1 modulates host translation machinery	Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
	ERGIC3	ERGIC and golgi 3
	ERRFI1	ERBB receptor feedback inhibitor 1

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