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Novel |
ATL1 |
atlastin GTPase 1 |
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- Hereditary spastic paraplegia (SPG)
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Novel |
EML2 |
EMAP like 2 |
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Novel |
ERO1A |
endoplasmic reticulum oxidoreductase 1 alpha |
- Detoxification of Reactive Oxygen Species
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Novel |
MIS12 |
MIS12 kinetochore complex component |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- EML4 and NUDC in mitotic spindle formation
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EZH2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
- PRC2 methylates histones and DNA
- Oxidative Stress Induced Senescence
- PKMTs methylate histone lysines
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- Transcriptional Regulation by E2F6
- HCMV Early Events
- Defective pyroptosis
- Negative Regulation of CDH1 Gene Transcription
- Regulation of PD-L1(CD274) transcription
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NEDD8 |
NEDD8 ubiquitin like modifier |
- TGF-beta receptor signaling activates SMADs
- UCH proteinases
- Cargo recognition for clathrin-mediated endocytosis
- Neddylation
- Iron uptake and transport
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RBX1 |
ring-box 1 |
- Recognition of DNA damage by PCNA-containing replication complex
- Prolactin receptor signaling
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- Vif-mediated degradation of APOBEC3G
- Degradation of beta-catenin by the destruction complex
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Degradation of DVL
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- DNA Damage Recognition in GG-NER
- Formation of Incision Complex in GG-NER
- Dual Incision in GG-NER
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Orc1 removal from chromatin
- Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- Regulation of RUNX2 expression and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Potential therapeutics for SARS
- Regulation of BACH1 activity
- Nuclear events stimulated by ALK signaling in cancer
- KEAP1-NFE2L2 pathway
- GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
- Antigen processing: Ubiquitination & Proteasome degradation
- Evasion by RSV of host interferon responses
- GSK3B-mediated proteasomal degradation of PD-L1(CD274)
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
- Degradation of CRY and PER proteins
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
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RIC8B |
RIC8 guanine nucleotide exchange factor B |
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SELENOK |
selenoprotein K |
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SELENOS |
selenoprotein S |
- E3 ubiquitin ligases ubiquitinate target proteins
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STRN4 |
striatin 4 |
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USP1 |
ubiquitin specific peptidase 1 |
- Recognition of DNA damage by PCNA-containing replication complex
- Fanconi Anemia Pathway
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