KLHDC2 and EML2

		KLHDC2	EML2
Description		kelch domain containing 2	EMAP like 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Nuclear Membrane	Cytoplasm Spindle Cytoskeleton Microtubule Microtubule Associated Complex Mitotic Spindle
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding Microtubule Binding Tubulin Binding
	Biological Process	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway	Microtubule Cytoskeleton Organization Visual Perception Sensory Perception Of Sound Regulation Of Microtubule Nucleation Negative Regulation Of Microtubule Polymerization
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Drugs
Diseases
GWAS			Fruit consumption ( 32066663) Hemoglobin A1c levels ( 29403010) Subcutaneous adipose tissue ( 22589738) Type 2 diabetes ( 32499647)
Interacting Genes		8 interacting genes: EZH2 NEDD8 RBX1 RIC8B SELENOK SELENOS STRN4 USP1	12 interacting genes: BPIFA1 EIF3F EXD1 IFI35 IFT88 PLEKHF2 PTTG2 REL RFC5 SNX32 SPANXA1 SPANXA2
Entrez ID		23588	24139
HPRD ID		08824	16860
Ensembl ID		ENSG00000165516	ENSG00000125746
Uniprot IDs		Q9Y2U9	O95834
PDB IDs		6DO3 6DO4 6DO5 8EBL 8EBM 8EBN 8PIF 8SGE 8SGF 8SH2 8UXS 9BC9 9BCA 9BCC	4CGB
Enriched GO Terms of Interacting Partners?		Response To Oxidative Stress Protein Modification Process Hepatocyte Homeostasis Cellular Response To Stress Cellular Response To Oxidative Stress Protein Neddylation Positive Regulation Of Error-prone Translesion Synthesis Cell Redox Homeostasis Response To Endoplasmic Reticulum Stress Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Subcompartment Cellular Response To Chemical Stress
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