FCGR2A - Wiki-Pi

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37 interactions involving FCGR2A - Fc gamma receptor IIa found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases

Novel	Symbol	Description	Pathways Hide	Drugs Hide	Diseases Hide
Novel	ACTR2	actin related protein 2	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Novel	F5	coagulation factor V	Platelet degranulation Common Pathway of Fibrin Clot Formation COPII-mediated vesicle transport Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation	Drotrecogin alfa Thrombomodulin Alfa Thrombin Protein C Human thrombin Thrombin alfa Protein S human Anti-inhibitor coagulant complex	Factor V deficiency; Owren disease Inherited thrombophilia
Novel	FAM3B	FAM3 metabolism regulating signaling molecule B
Novel	FCER1A	Fc epsilon receptor Ia	Fc epsilon receptor (FCERI) signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization FCERI mediated NF-kB activation	Omalizumab Benzylpenicilloyl polylysine TNX-901
Novel	FCER1G	Fc epsilon receptor Ig	GPVI-mediated activation cascade Cell surface interactions at the vascular wall Fc epsilon receptor (FCERI) signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization FCERI mediated NF-kB activation Dectin-2 family Dectin-2 family Neutrophil degranulation Platelet Adhesion to exposed collagen	Benzylpenicilloyl polylysine
Novel	FCGR2B	Fc gamma receptor IIb	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Etanercept Human immunoglobulin G Abciximab Tositumomab Alemtuzumab Antithymocyte immunoglobulin (rabbit) Palivizumab Daclizumab Bevacizumab Sarilumab	Systemic lupus erythematosus
Novel	FCGR3A	Fc gamma receptor IIIa	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis	Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Alefacept Palivizumab Daclizumab Bevacizumab Catumaxomab Sarilumab Benralizumab Amivantamab	NK cell defects, including the following disease: CD16 deficiency Systemic lupus erythematosus
Novel	LIMK2	LIM domain kinase 2	EPHB-mediated forward signaling Sema4D induced cell migration and growth-cone collapse RHO GTPases Activate ROCKs	Fostamatinib
Novel	MGST3	microsomal glutathione S-transferase 3	Glutathione conjugation Aflatoxin activation and detoxification	Glutathione
Novel	TARDBP	TAR DNA binding protein			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
Novel	TMCO1	transmembrane and coiled-coil domains 1
	ADAM33	ADAM metallopeptidase domain 33	Regulation of CDH11 function		Asthma
	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	Synthesis of PA
	BLK	BLK proto-oncogene, Src family tyrosine kinase	RUNX1 regulates transcription of genes involved in BCR signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Fostamatinib Zanubrutinib	Maturity onset diabetes of the young (MODY)
	CDIPT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	Synthesis of PI	scyllo-inositol
	CMTM5	CKLF like MARVEL transmembrane domain containing 5
	CRP	C-reactive protein	Classical antibody-mediated complement activation	N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRx-139	Systemic lupus erythematosus
	CRYAB	crystallin alpha B	HSF1-dependent transactivation		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	CS-GAG biosynthesis
	CXCL9	C-X-C motif chemokine ligand 9	Chemokine receptors bind chemokines G alpha (i) signalling events

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