| Novel |
ANTXR2
|
ANTXR cell adhesion molecule 2 |
|
|
- Infantile systemic hyalinosis and juvenile hyaline fibromatosis
|
| Novel |
ARHGAP20
|
Rho GTPase activating protein 20 |
- RHOA GTPase cycle
- CDC42 GTPase cycle
- RAC1 GTPase cycle
|
|
|
| Novel |
ARL2BP
|
ARF like GTPase 2 binding protein |
- Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
|
|
|
| Novel |
BCO2
|
beta-carotene oxygenase 2 |
- Retinoid metabolism and transport
|
|
|
| Novel |
CUL5
|
cullin 5 |
- Vif-mediated degradation of APOBEC3G
- Downregulation of ERBB2 signaling
- Neddylation
- Inactivation of CSF3 (G-CSF) signaling
- Inactivation of CSF3 (G-CSF) signaling
- Antigen processing: Ubiquitination & Proteasome degradation
- Evasion by RSV of host interferon responses
|
|
|
| Novel |
DES
|
desmin |
- Striated Muscle Contraction
|
|
- Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
- Dilated cardiomyopathy (DCM)
- Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
- Scapuloperoneal myopathy (SPM)
|
| Novel |
DSC3
|
desmocollin 3 |
- Keratinization
- Formation of the cornified envelope
|
|
- Hypotrichosis and recurrent skin vesicles
|
| Novel |
HSPB2
|
heat shock protein family B (small) member 2 |
|
|
|
| Novel |
IGFBP6
|
insulin like growth factor binding protein 6 |
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
|
|
|
| Novel |
NPAT
|
nuclear protein, coactivator of histone transcription |
|
|
|
| Novel |
PGR
|
progesterone receptor |
- Nuclear signaling by ERBB4
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- Nuclear Receptor transcription pathway
- SUMOylation of intracellular receptors
- Estrogen-dependent gene expression
- Developmental Lineage of Mammary Gland Luminal Epithelial Cells
- Developmental Lineage of Mammary Gland Alveolar Cells
|
- Etonogestrel
- Desogestrel
- Megestrol acetate
- Levonorgestrel
- Dydrogesterone
- Progesterone
- Spironolactone
- Lindane
- Fluticasone propionate
- Medroxyprogesterone acetate
- Mitotane
- Norethisterone
- Mometasone
- Ethynodiol diacetate
- Mifepristone
- Norgestimate
- Drospirenone
- Danazol
- Oxybenzone
- Allylestrenol
- Phthalic Acid
- Metribolone
- Tanaproget
- Telapristone acetate
- Asoprisnil
- Norelgestromin
- Gestodene
- Hydroxyprogesterone caproate
- Ulipristal
- Fluticasone furoate
- Dienogest
- Medrogestone
- Norgestrel
- Homosalate
- Enzacamene
- Gestrinone
- Darolutamide
- Demegestone
- Fluticasone
- Mometasone furoate
- Segesterone acetate
|
|
| Novel |
PTS
|
6-pyruvoyltetrahydropterin synthase |
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
|
- Mycophenolate mofetil
- Biopterin
|
- Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
|
| Novel |
SLN
|
sarcolipin |
- Ion homeostasis
- Ion transport by P-type ATPases
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
FBXO7
|
F-box protein 7 |
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
RNF10
|
ring finger protein 10 |
|
|
|
|
SIRPA
|
signal regulatory protein alpha |
- Cell surface interactions at the vascular wall
- Signal regulatory protein family interactions
- Signal regulatory protein family interactions
- Neutrophil degranulation
|
|
|