Search Results for: CASP10

36 interactions involving CASP10 - caspase 10 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel BMPR2 bone morphogenetic protein receptor type 2
  • Signaling by BMP
  • Dibotermin alfa
  • Fostamatinib
Novel ERBB4 erb-b2 receptor tyrosine kinase 4
  • Afatinib
  • Fostamatinib
  • Brigatinib
  • Zanubrutinib
Novel IGFBP2 insulin like growth factor binding protein 2
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Novel NPTX1 neuronal pentraxin 1
Novel SCARB1 scavenger receptor class B member 1
  • Phosphatidyl serine
Novel YBX3 Y-box binding protein 3
BFAR bifunctional apoptosis regulator
BID BH3 interacting domain death agonist
  • Activation of BAD and translocation to mitochondria
  • Activation and oligomerization of BAK protein
  • BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
  • Activation, translocation and oligomerization of BAX
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
  • Activation, myristolyation of BID and translocation to mitochondria
CASP1 caspase 1
  • NOD1/2 Signaling Pathway
  • Interleukin-1 processing
  • Pyroptosis
  • TP53 Regulates Transcription of Caspase Activators and Caspases
  • The NLRP3 inflammasome
  • The AIM2 inflammasome
  • The IPAF inflammasome
  • Interleukin-37 signaling
  • Purinergic signaling in leishmaniasis infection
  • SARS-CoV-1 activates/modulates innate immune responses
  • Acetylsalicylic acid
  • Minocycline
  • Pralnacasan
  • LAX-101
  • Emricasan
  • VX-765
  • 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE
  • Z-Val-Ala-Asp fluoromethyl ketone
  • 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID
CASP14 caspase 14
  • Formation of the cornified envelope
  • Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
CASP2 caspase 2
  • NOD1/2 Signaling Pathway
  • NADE modulates death signalling
  • TP53 Regulates Transcription of Caspase Activators and Caspases
CASP3 caspase 3
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • Apoptotic cleavage of cellular proteins
  • SMAC, XIAP-regulated apoptotic response
  • Apoptosis induced DNA fragmentation
  • Degradation of the extracellular matrix
  • Signaling by Hippo
  • NADE modulates death signalling
  • Stimulation of the cell death response by PAK-2p34
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Apoptotic cleavage of cell adhesion proteins
  • Caspase activation via Dependence Receptors in the absence of ligand
  • Caspase activation via Dependence Receptors in the absence of ligand
  • Other interleukin signaling
  • Pyroptosis
  • CASP4-mediated substrate cleavage
  • CASP5-mediated substrate cleavage
  • Pamidronic acid
  • Acetylsalicylic acid
  • Minocycline
  • 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid
  • Emricasan
  • Incadronic acid
  • 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
  • methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate
  • 1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE
  • [N-(3-dibenzylcarbamoyl-oxiranecarbonyl)-hydrazino]-acetic acid
  • 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID
  • (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
  • (1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
  • N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide
  • Tributyrin
  • Oleandrin
  • PAC-1
  • Glycyrrhizic acid
CASP4 caspase 4
  • NOD1/2 Signaling Pathway
  • Pyroptosis
  • CASP4 inflammasome assembly
  • Microbial factors inhibit CASP4 activity
  • CASP4-mediated substrate cleavage
  • Incadronic acid
CASP6 caspase 6
  • Apoptotic cleavage of cellular proteins
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Breakdown of the nuclear lamina
  • TP53 Regulates Transcription of Caspase Activators and Caspases
CASP7 caspase 7
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • Apoptotic cleavage of cellular proteins
  • SMAC, XIAP-regulated apoptotic response
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Fica
  • Emricasan
  • Incadronic acid
CASP8 caspase 8
  • Apoptotic cleavage of cellular proteins
  • Caspase activation via Death Receptors in the presence of ligand
  • NOD1/2 Signaling Pathway
  • TRIF-mediated programmed cell death
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Regulation by c-FLIP
  • RIPK1-mediated regulated necrosis
  • CASP8 activity is inhibited
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • CLEC7A/inflammasome pathway
  • Regulation of necroptotic cell death
  • Dimerization of procaspase-8
  • Activation, myristolyation of BID and translocation to mitochondria
  • Apoptotic execution phase
  • FasL/ CD95L signaling
  • TRAIL signaling
  • TLR3-mediated TICAM1-dependent programmed cell death
  • NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
  • Microbial modulation of RIPK1-mediated regulated necrosis
  • Defective RIPK1-mediated regulated necrosis
  • Regulation of NF-kappa B signaling
  • Trichostatin A
  • AN-9
  • Bryostatin 1
  • Bardoxolone
  • Oleandrin
  • Autoimmune lymphoproliferative syndromes (ALPS), including the following five diseases: CD95 (Fas) defect, ALPS type 1a; CD95L (Fas ligand) defect, ALPS type 1b; Caspase 10 defect, ALPS type 2a; Caspase 8 defext, ALPS type 2b; Activaing N-Ras defect, N-Ras ALPS
CASP8AP2 caspase 8 associated protein 2
  • SUMOylation of transcription cofactors
CASP9 caspase 9
  • Formation of apoptosome
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • NOD1/2 Signaling Pathway
  • AKT phosphorylates targets in the cytosol
  • Caspase activation via Dependence Receptors in the absence of ligand
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Regulation of the apoptosome activity
  • Regulation of the apoptosome activity
  • Pamidronic acid
CCAR1 cell division cycle and apoptosis regulator 1
  • mRNA Splicing - Major Pathway
CFLAR CASP8 and FADD like apoptosis regulator
  • TRAIL signaling

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