C5 - Wiki-Pi

Search Results for: C5

Can't find the interaction you're looking for? Try the advanced search

31 interactions involving C5 - complement C5 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases

Novel	Symbol	Description	Pathways Hide	Drugs Hide	Diseases Hide
Novel	LIMK1	LIM domain kinase 1	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling Sema3A PAK dependent Axon repulsion Sema3A PAK dependent Axon repulsion Sema4D induced cell migration and growth-cone collapse RHO GTPases Activate ROCKs RHO GTPases activate PAKs	Dabrafenib Fostamatinib
Novel	LRSAM1	leucine rich repeat and sterile alpha motif containing 1	Antigen processing: Ubiquitination & Proteasome degradation
Novel	NEK6	NIMA related kinase 6	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Novel	PIGP	phosphatidylinositol glycan anchor biosynthesis class P	Synthesis of glycosylphosphatidylinositol (GPI)
Novel	PRDM16	PR/SET domain 16	PKMTs methylate histone lysines Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Novel	PRKCZ	protein kinase C zeta	GPVI-mediated activation cascade TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) VEGFR2 mediated cell proliferation RHO GTPases Activate NADPH Oxidases Estrogen-stimulated signaling through PRKCZ Estrogen-stimulated signaling through PRKCZ	Tamoxifen Staurosporine Dequalinium Benzoyl peroxide
Novel	SARDH	sarcosine dehydrogenase	Choline catabolism
Novel	SLC10A2	solute carrier family 10 member 2	Recycling of bile acids and salts	Volixibat Maralixibat Odevixibat	Primary bile acid malabsorption
Novel	SPTAN1	spectrin alpha, non-erythrocytic 1	Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport RHOU GTPase cycle RHOV GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea		Early infantile epileptic encephalopathy; Ohtahara syndrome
	ANKS6	ankyrin repeat and sterile alpha motif domain containing 6
	AQP6	aquaporin 6	Passive transport by Aquaporins
	C2	complement C2	Initial triggering of complement Activation of C3 and C5 Regulation of Complement cascade		Systemic lupus erythematosus Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
	C3	complement C3	Alternative complement activation Activation of C3 and C5 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Peptide ligand-binding receptors Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (i) signalling events Neutrophil degranulation Post-translational protein phosphorylation Purinergic signaling in leishmaniasis infection Regulation of Complement cascade	Human immunoglobulin G Zinc S-Hydroxycysteine Mirococept Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form Pegcetacoplan	Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
	C5AR1	complement C5a receptor 1	Peptide ligand-binding receptors G alpha (i) signalling events Neutrophil degranulation Regulation of Complement cascade	Avacopan
	C6	complement C6	Terminal pathway of complement Regulation of Complement cascade		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	C7	complement C7	Terminal pathway of complement Regulation of Complement cascade		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	C8B	complement C8 beta chain	Terminal pathway of complement Regulation of Complement cascade	Zinc Copper Zinc acetate	Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
	CPB2	carboxypeptidase B2	Metabolism of Angiotensinogen to Angiotensins Regulation of Complement cascade	AZD-9684 Prothrombin
	CPLX4	complexin 4
	CPN1	carboxypeptidase N subunit 1	Regulation of Complement cascade	Zinc ORE-1001 Zinc acetate Zinc chloride Zinc sulfate, unspecified form

Page 1 out of 2 pages