HIV - New-wiki

Novel	Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide	Drugs 2 Hide	Diseases 1 Hide	Diseases 2 Hide
Novel Novel	Symbols HTATSF1 and ZNF512B	Name 1 HIV-1 Tat specific factor 1	Name2 zinc finger protein 512B	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 RHOV GTPase cycle	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols HTATSF1 and MAP1LC3A	Name 1 HIV-1 Tat specific factor 1	Name2 microtubule associated protein 1 light chain 3 alpha	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols PIEZO1 and FBXO7	Name 1 piezo type mechanosensitive ion channel component 1 (Er blood group)	Name2 F-box protein 7	Pathway 1 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Mechanical load activates signaling by PIEZO1 and integrins in osteocytes Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Pathway 2 Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Drugs 1	Drugs 2	Diseases 1	Diseases 2 Parkinson's disease (PD)
Novel Novel	Symbols DHODH and MT2A	Name 1 dihydroorotate dehydrogenase (quinone)	Name2 metallothionein 2A	Pathway 1 Pyrimidine biosynthesis	Pathway 2 Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling	Drugs 1 Leflunomide Atovaquone Orotic acid Capric dimethyl amine oxide Flavin mononucleotide Brequinar Analog Brequinar Dodecyldimethylamine N-oxide 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid SC12267 Manitimus (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide 3,6,9,12,15-PENTAOXATRICOSAN-1-OL Teriflunomide	Drugs 2 Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Diseases 1	Diseases 2
Novel Novel	Symbols EHHADH and HTATIP2	Name 1 enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Name2 HIV-1 Tat interactive protein 2	Pathway 1 Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Pathway 2	Drugs 1 NADH	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel Novel	Symbols CTNNA2 and CTNNBIP1	Name 1 catenin alpha 2	Name2 catenin beta interacting protein 1	Pathway 1 Myogenesis Myogenesis	Pathway 2 Deactivation of the beta-catenin transactivating complex	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols TMED7 and TMPRSS3	Name 1 transmembrane p24 trafficking protein 7	Name2 transmembrane serine protease 3	Pathway 1 COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols GPC5 and DCPS	Name 1 glypican 5	Name2 decapping enzyme, scavenger	Pathway 1 Glycosaminoglycan-protein linkage region biosynthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Release of Hh-Np from the secreting cell Attachment and Entry Attachment and Entry Retinoid metabolism and transport Respiratory syncytial virus (RSV) attachment and entry RSV-host interactions	Pathway 2 mRNA decay by 3' to 5' exoribonuclease	Drugs 1	Drugs 2 7-methyl-GpppA 7-methyl-7,8-dihydroguanosine-5'-diphosphate 7-methyl-5'-guanylic acid 7-methyl-guanosine-5'-triphosphate-5'-guanosine 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine	Diseases 1	Diseases 2
Novel Novel	Symbols FUT9 and TSSK3	Name 1 fucosyltransferase 9	Name2 testis specific serine kinase 3	Pathway 1 Lewis blood group biosynthesis	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols WBP4 and HTATSF1	Name 1 WW domain binding protein 4	Name2 HIV-1 Tat specific factor 1	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 mRNA Splicing - Major Pathway	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols RECK and ZNF704	Name 1 reversion inducing cysteine rich protein with kazal motifs	Name2 zinc finger protein 704	Pathway 1 Post-translational modification: synthesis of GPI-anchored proteins	Pathway 2 Generic Transcription Pathway	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols GMCL1 and IL17F	Name 1 germ cell-less 1, spermatogenesis associated	Name2 interleukin 17F	Pathway 1	Pathway 2 Interleukin-17 signaling Interleukin-4 and Interleukin-13 signaling SARS-CoV-2 activates/modulates innate and adaptive immune responses	Drugs 1	Drugs 2 Bimekizumab	Diseases 1	Diseases 2 Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
Novel Novel	Symbols GET1 and HTATIP2	Name 1 guided entry of tail-anchored proteins factor 1	Name2 HIV-1 Tat interactive protein 2	Pathway 1 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Pathway 2	Drugs 1	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel Novel	Symbols SLC18A1 and HTATIP2	Name 1 solute carrier family 18 member A1	Name2 HIV-1 Tat interactive protein 2	Pathway 1	Pathway 2	Drugs 1 Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel Novel	Symbols GCNT1 and GOLPH3	Name 1 glucosaminyl (N-acetyl) transferase 1	Name2 golgi phosphoprotein 3	Pathway 1 O-linked glycosylation of mucins	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols CCRL2 and ARLN	Name 1 C-C motif chemokine receptor like 2	Name2 allregulin	Pathway 1 Chemokine receptors bind chemokines	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols FARP1 and PIH1D1	Name 1 FERM, ARH/RhoGEF and pleckstrin domain protein 1	Name2 PIH1 domain containing 1	Pathway 1 RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOF GTPase cycle	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols SLC39A11 and FAM241B	Name 1 solute carrier family 39 member 11	Name2 family with sequence similarity 241 member B	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols SMOX and MCPH1	Name 1 spermine oxidase	Name2 microcephalin 1	Pathway 1	Pathway 2 Condensation of Prophase Chromosomes	Drugs 1 Spermine MDL72527	Drugs 2	Diseases 1	Diseases 2 Primary microcephaly (MCPH)
Novel Novel	Symbols COL13A1 and MTDH	Name 1 collagen type XIII alpha 1 chain	Name2 metadherin	Pathway 1 Collagen degradation Collagen biosynthesis and modifying enzymes Integrin cell surface interactions Collagen chain trimerization	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols HTATSF1 and ZNF512B	Name 1 HIV-1 Tat specific factor 1	Name2 zinc finger protein 512B	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 RHOV GTPase cycle	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols HTATSF1 and MAP1LC3A	Name 1 HIV-1 Tat specific factor 1	Name2 microtubule associated protein 1 light chain 3 alpha	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols PIEZO1 and FBXO7	Name 1 piezo type mechanosensitive ion channel component 1 (Er blood group)	Name2 F-box protein 7	Pathway 1 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Mechanical load activates signaling by PIEZO1 and integrins in osteocytes Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Pathway 2 Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Drugs 1	Drugs 2	Diseases 1	Diseases 2 Parkinson's disease (PD)
Novel	Symbols DHODH and MT2A	Name 1 dihydroorotate dehydrogenase (quinone)	Name2 metallothionein 2A	Pathway 1 Pyrimidine biosynthesis	Pathway 2 Metallothioneins bind metals Metallothioneins bind metals Interferon gamma signaling	Drugs 1 Leflunomide Atovaquone Orotic acid Capric dimethyl amine oxide Flavin mononucleotide Brequinar Analog Brequinar Dodecyldimethylamine N-oxide 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid SC12267 Manitimus (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide 3,6,9,12,15-PENTAOXATRICOSAN-1-OL Teriflunomide	Drugs 2 Zinc Silver Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Diseases 1	Diseases 2
Novel	Symbols EHHADH and HTATIP2	Name 1 enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Name2 HIV-1 Tat interactive protein 2	Pathway 1 Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import	Pathway 2	Drugs 1 NADH	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel	Symbols CTNNA2 and CTNNBIP1	Name 1 catenin alpha 2	Name2 catenin beta interacting protein 1	Pathway 1 Myogenesis Myogenesis	Pathway 2 Deactivation of the beta-catenin transactivating complex	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols TMED7 and TMPRSS3	Name 1 transmembrane p24 trafficking protein 7	Name2 transmembrane serine protease 3	Pathway 1 COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols GPC5 and DCPS	Name 1 glypican 5	Name2 decapping enzyme, scavenger	Pathway 1 Glycosaminoglycan-protein linkage region biosynthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Release of Hh-Np from the secreting cell Attachment and Entry Attachment and Entry Retinoid metabolism and transport Respiratory syncytial virus (RSV) attachment and entry RSV-host interactions	Pathway 2 mRNA decay by 3' to 5' exoribonuclease	Drugs 1	Drugs 2 7-methyl-GpppA 7-methyl-7,8-dihydroguanosine-5'-diphosphate 7-methyl-5'-guanylic acid 7-methyl-guanosine-5'-triphosphate-5'-guanosine 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine	Diseases 1	Diseases 2
Novel	Symbols FUT9 and TSSK3	Name 1 fucosyltransferase 9	Name2 testis specific serine kinase 3	Pathway 1 Lewis blood group biosynthesis	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols WBP4 and HTATSF1	Name 1 WW domain binding protein 4	Name2 HIV-1 Tat specific factor 1	Pathway 1 mRNA Splicing - Major Pathway	Pathway 2 mRNA Splicing - Major Pathway	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols RECK and ZNF704	Name 1 reversion inducing cysteine rich protein with kazal motifs	Name2 zinc finger protein 704	Pathway 1 Post-translational modification: synthesis of GPI-anchored proteins	Pathway 2 Generic Transcription Pathway	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols GMCL1 and IL17F	Name 1 germ cell-less 1, spermatogenesis associated	Name2 interleukin 17F	Pathway 1	Pathway 2 Interleukin-17 signaling Interleukin-4 and Interleukin-13 signaling SARS-CoV-2 activates/modulates innate and adaptive immune responses	Drugs 1	Drugs 2 Bimekizumab	Diseases 1	Diseases 2 Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
Novel	Symbols GET1 and HTATIP2	Name 1 guided entry of tail-anchored proteins factor 1	Name2 HIV-1 Tat interactive protein 2	Pathway 1 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Pathway 2	Drugs 1	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel	Symbols SLC18A1 and HTATIP2	Name 1 solute carrier family 18 member A1	Name2 HIV-1 Tat interactive protein 2	Pathway 1	Pathway 2	Drugs 1 Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine	Drugs 2 Polyethylene glycol 400	Diseases 1	Diseases 2
Novel	Symbols GCNT1 and GOLPH3	Name 1 glucosaminyl (N-acetyl) transferase 1	Name2 golgi phosphoprotein 3	Pathway 1 O-linked glycosylation of mucins	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols CCRL2 and ARLN	Name 1 C-C motif chemokine receptor like 2	Name2 allregulin	Pathway 1 Chemokine receptors bind chemokines	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols FARP1 and PIH1D1	Name 1 FERM, ARH/RhoGEF and pleckstrin domain protein 1	Name2 PIH1 domain containing 1	Pathway 1 RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOF GTPase cycle	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols SLC39A11 and FAM241B	Name 1 solute carrier family 39 member 11	Name2 family with sequence similarity 241 member B	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols SMOX and MCPH1	Name 1 spermine oxidase	Name2 microcephalin 1	Pathway 1	Pathway 2 Condensation of Prophase Chromosomes	Drugs 1 Spermine MDL72527	Drugs 2	Diseases 1	Diseases 2 Primary microcephaly (MCPH)
Novel	Symbols COL13A1 and MTDH	Name 1 collagen type XIII alpha 1 chain	Name2 metadherin	Pathway 1 Collagen degradation Collagen biosynthesis and modifying enzymes Integrin cell surface interactions Collagen chain trimerization	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2

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