Search Results for: ELOB

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
EPOR erythropoietin receptor
  • Signaling by Erythropoietin
  • Signaling by Erythropoietin
  • Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
  • Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
  • Erythropoietin activates Phospholipase C gamma (PLCG)
  • Erythropoietin activates STAT5
  • Erythropoietin activates RAS
  • Erythropoietin activates RAS
  • Darbepoetin alfa
  • Erythropoietin
  • Dibromotyrosine
  • Peginesatide
  • Methoxy polyethylene glycol-epoetin beta
  • Congenital polycythemia; Familial erythrocytosis (ECYT)
GHR growth hormone receptor
  • Prolactin receptor signaling
  • Growth hormone receptor signaling
  • Growth hormone receptor signaling
  • Somatotropin
  • Pegvisomant
  • Somatrem
  • Somapacitan
  • Lonapegsomatropin
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GPS1 G protein pathway suppressor 1
  • DNA Damage Recognition in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Cargo recognition for clathrin-mediated endocytosis
  • Neddylation
  • RHOBTB1 GTPase cycle
LRRC41 leucine rich repeat containing 41
  • Neddylation
  • RHOBTB3 ATPase cycle
  • Antigen processing: Ubiquitination & Proteasome degradation
MRPL53 mitochondrial ribosomal protein L53
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
  • Mitochondrial ribosome-associated quality control
PRAME PRAME nuclear receptor transcriptional regulator
RACK1 receptor for activated C kinase 1
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR1-mediated ceramide production
  • Degradation of CDH1
  • Copper
RBX1 ring-box 1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Prolactin receptor signaling
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Vif-mediated degradation of APOBEC3G
  • Degradation of beta-catenin by the destruction complex
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • Degradation of DVL
  • Degradation of GLI1 by the proteasome
  • Degradation of GLI2 by the proteasome
  • GLI3 is processed to GLI3R by the proteasome
  • Hedgehog 'on' state
  • Regulation of RAS by GAPs
  • DNA Damage Recognition in GG-NER
  • Formation of Incision Complex in GG-NER
  • Dual Incision in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Orc1 removal from chromatin
  • Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
  • FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
  • Regulation of RUNX2 expression and activity
  • Neddylation
  • Regulation of expression of SLITs and ROBOs
  • Interleukin-1 signaling
  • Negative regulation of NOTCH4 signaling
  • Potential therapeutics for SARS
  • Regulation of BACH1 activity
  • Nuclear events stimulated by ALK signaling in cancer
  • KEAP1-NFE2L2 pathway
  • GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Evasion by RSV of host interferon responses
  • GSK3B-mediated proteasomal degradation of PD-L1(CD274)
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Degradation of CRY and PER proteins
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
SOCS1 suppressor of cytokine signaling 1
  • Interleukin-7 signaling
  • Regulation of KIT signaling
  • MyD88:MAL(TIRAP) cascade initiated on plasma membrane
  • Interleukin-4 and Interleukin-13 signaling
  • Interferon gamma signaling
  • Regulation of IFNG signaling
  • Interferon alpha/beta signaling
  • Regulation of IFNA/IFNB signaling
  • Signaling by CSF3 (G-CSF)
  • Inactivation of CSF3 (G-CSF) signaling
  • Inactivation of CSF3 (G-CSF) signaling
  • Growth hormone receptor signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
SOCS3 suppressor of cytokine signaling 3
  • Interleukin-6 signaling
  • Signaling by Leptin
  • Interleukin-4 and Interleukin-13 signaling
  • Interferon gamma signaling
  • Regulation of IFNG signaling
  • PTK6 Activates STAT3
  • RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
  • Neddylation
  • Interferon alpha/beta signaling
  • Regulation of IFNA/IFNB signaling
  • Signaling by CSF3 (G-CSF)
  • Inactivation of CSF3 (G-CSF) signaling
  • Inactivation of CSF3 (G-CSF) signaling
  • Growth hormone receptor signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
SOCS6 suppressor of cytokine signaling 6
  • Regulation of KIT signaling
  • Neddylation
  • Negative regulation of FLT3
VHL von Hippel-Lindau tumor suppressor
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • SUMOylation of ubiquitinylation proteins
  • Neddylation
  • Replication of the SARS-CoV-1 genome
  • Replication of the SARS-CoV-2 genome
  • RHOBTB3 ATPase cycle
  • Antigen processing: Ubiquitination & Proteasome degradation
  • von Hippel-Lindau syndrome
  • Congenital polycythemia; Familial erythrocytosis (ECYT)
  • Renal cell carcinoma
ZYG11B zyg-11 family member B, cell cycle regulator

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