| Novel |
TOP1MT
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DNA topoisomerase I mitochondrial |
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| Novel |
ZNF707
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zinc finger protein 707 |
- Generic Transcription Pathway
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AQP6
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aquaporin 6 |
- Passive transport by Aquaporins
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CD79A
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CD79a molecule |
- CD22 mediated BCR regulation
- Potential therapeutics for SARS
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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- Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
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CNIH4
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cornichon family member 4 |
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CYB561
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cytochrome b561 |
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DYNLL1
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dynein light chain LC8-type 1 |
- Activation of BIM and translocation to mitochondria
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Macroautophagy
- MHC class II antigen presentation
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- Intraflagellar transport
- RHO GTPases Activate Formins
- Neutrophil degranulation
- COPI-mediated anterograde transport
- COPI-independent Golgi-to-ER retrograde traffic
- Mitotic Prometaphase
- AURKA Activation by TPX2
- HCMV Early Events
- Aggrephagy
- Aggrephagy
- EML4 and NUDC in mitotic spindle formation
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EBP
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EBP cholestenol delta-isomerase |
- Cholesterol biosynthesis via desmosterol
- Cholesterol biosynthesis via lathosterol
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ELOVL4
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ELOVL fatty acid elongase 4 |
- Synthesis of very long-chain fatty acyl-CoAs
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- Stargardt disease (STGD); Fundus flavimaculatus
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ELOVL5
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ELOVL fatty acid elongase 5 |
- Linoleic acid (LA) metabolism
- alpha-linolenic acid (ALA) metabolism
- Synthesis of very long-chain fatty acyl-CoAs
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
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GPR152
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G protein-coupled receptor 152 |
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JAGN1
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jagunal vesicle mediated transporter 1 |
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LEPROTL1
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leptin receptor overlapping transcript like 1 |
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LMNA
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lamin A/C |
- XBP1(S) activates chaperone genes
- Signaling by BRAF and RAF1 fusions
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- Mandibuloacral dysplasia
- Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
- Emery-Dreifuss muscular dystrophy
- Dilated cardiomyopathy (DCM)
- Limb-girdle muscular dystrophy (LGMD)
- Hutchinson-Gilford progeria syndrome
- Restrictive dermopathy
- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
- Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
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REEP4
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receptor accessory protein 4 |
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RETREG3
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reticulophagy regulator family member 3 |
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SEC11C
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SEC11 homolog C, signal peptidase complex subunit |
- SRP-dependent cotranslational protein targeting to membrane
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
- Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
- Synthesis, secretion, and deacylation of Ghrelin
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
- Maturation of hRSV A proteins
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SLC10A6
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solute carrier family 10 member 6 |
- SLC-mediated bile acid transport
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SLC35H1
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solute carrier family 35 member H1 |
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SLC71A2
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solute carrier family 71 member 2 |
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