TSNARE1 and ZNF707

		TSNARE1	ZNF707
Description		t-SNARE domain containing 1	zinc finger protein 707
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Endomembrane System Membrane SNARE Complex	Nucleus
	Molecular Function	SNARE Binding SNAP Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder x sex interaction ( 34099189) Body size at age 10 ( 32376654) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Feeling nervous ( 29500382) Feeling tense ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Monoclonal gammopathy of undetermined significance ( 30737484) Schizophrenia ( 25056061 28991256 29483656 23974872 30285260) Systolic blood pressure ( 30578418 30224653)
Interacting Genes		27 interacting genes: AQP6 CD79A CNIH4 CYB561 DYNLL1 EBP ELOVL4 ELOVL5 GPR152 JAGN1 LEPROTL1 LMNA REEP4 RETREG3 SEC11C SLC10A6 SLC35H1 SLC71A2 STX1A TM4SF19 TMEM229B TMEM51 TMEM86B TMX2 VEZT YIPF4 ZDHHC15	8 interacting genes: CASP8 CCNDBP1 KRTAP10-5 KRTAP10-7 MDFI NDEL1 RALBP1 STX1A
Entrez ID		203062	286075
HPRD ID		08708	14162
Ensembl ID		ENSG00000171045	ENSG00000181135
Uniprot IDs		A0AVG3 E5RHT3 Q6P186 Q96NA8	Q96C28
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Endoplasmic Reticulum Organization Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Nuclear Envelope Organization Long-chain Fatty-acyl-CoA Metabolic Process Myosin Binding Fatty-acyl-CoA Biosynthetic Process	Identical Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Synaptic Vesicle SNAP Receptor Activity SNARE Complex Myosin Head/neck Binding SNARE Binding Vesicle Docking Doxorubicin Transport Organelle Localization By Membrane Tethering Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Organelle Membrane Fusion Organelle Localization Membrane Docking Vesicle Fusion Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Neurofilament Cytoskeleton Keratin Filament Death Effector Domain Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Organelle Fusion Regulation Of GTPase Activity
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