TSNARE1 and CNIH4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSNARE1	CNIH4
Description		t-SNARE domain containing 1	cornichon family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptic Vesicle Endomembrane System Membrane SNARE Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	SNARE Binding SNAP Receptor Activity	Signaling Receptor Binding Protein Binding CCR5 Chemokine Receptor Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder x sex interaction ( 34099189) Body size at age 10 ( 32376654) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) Feeling nervous ( 29500382) Feeling tense ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence (MTAG) ( 29326435) Mental health study participation (completed survey) ( 31263887) Monoclonal gammopathy of undetermined significance ( 30737484) Schizophrenia ( 25056061 28991256 29483656 23974872 30285260) Systolic blood pressure ( 30578418 30224653)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) HDL cholesterol levels in HIV infection ( 33109212) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Major depressive disorder ( 21042317) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		27 interacting genes: AQP6 CD79A CNIH4 CYB561 DYNLL1 EBP ELOVL4 ELOVL5 GPR152 JAGN1 LEPROTL1 LMNA REEP4 RETREG3 SEC11C SLC10A6 SLC35H1 SLC71A2 STX1A TM4SF19 TMEM229B TMEM51 TMEM86B TMX2 VEZT YIPF4 ZDHHC15	4 interacting genes: GLP1R GPR25 TMEM14B TSNARE1
Entrez ID		203062	29097
HPRD ID		08708	13709
Ensembl ID		ENSG00000171045	ENSG00000143771
Uniprot IDs		A0AVG3 E5RHT3 Q6P186 Q96NA8	A6NLH6 Q9P003
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Endoplasmic Reticulum Organization Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Nuclear Envelope Organization Long-chain Fatty-acyl-CoA Metabolic Process Myosin Binding Fatty-acyl-CoA Biosynthetic Process	Glucagon-like Peptide 1 Receptor Activity Methionine Adenosyltransferase Regulator Activity Glucagon Receptor Activity Methionine Adenosyltransferase Complex S-adenosylmethionine Biosynthetic Process Response To Psychosocial Stress Post-translational Protein Targeting To Membrane, Translocation
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