CYTH3

Name	cytohesin 3
Structure
Interactors	10 interactors: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN
GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity
Pathways	Intra-Golgi traffic
Drugs	Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
GWAS	Asthma ( 27611488 ) Body mass index ( 26426971 ) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321 ) Shigella-associated diarrhea ( 33649051 )
Entrez ID	9265
HPRD ID	05469
Ensembl ID	ENSG00000008256
Uniprot IDs	B7Z2V9 O43739
PDB IDs	4KAX 6U3E 6U3G
GO Terms Enriched among Interactors ?	Cell Cortex Cytoplasm Macrophage Activation Regulation Of Cellular Respiration Presynaptic Endocytosis Synaptic Vesicle Endocytosis Regulation Of Endocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission